- Board of Visitors records, 1757/20231
- Carter Family Papers, 1667/1862, bulk 1792/18611
- Early Records of the Mount Vernon Ladies' Association, 1853/1951, bulk 1853/18751
- John Buchanan Floyd Papers, 1831/18621
- John Tyler Letter to Benjamin Ogle Tayloe, 18351
- John Tyler Letter to Henry A. Wise, 18551
- John Tyler Letter to Robert S. Stanard, 18191
- John Tyler Papers, 1840/19311
- Peter family papers, 1722/19321
- President John Tyler Letter and Engraving, 18421
- Tazewell Family Papers, 1797/18501
- Tyler Family Papers, Group A - H, Additions, 1821/19761
- Tyler Family Papers, Group A, 1716/19461
- Tyler Family Papers, Group H, 1750/19351