- A. E. Dick Howard papers, 1928/20171
- Addison H. Smith papers, 1917/1970, bulk 1917/19221
- Arthur J. Morris memorabilia, 1884/19921
- Beverley R. Tucker papers, 1886/19731
- Carl McFarland papers, 1920/19801
- Chisholm Foundation collection on Frank Gardiner Wisner, 1909/19971
- Coleman, Bromm, Kirschmann family papers, 1861/20181
- Cumming Family Papers, 1818/19921
- Ewing family memorabilia, 1892/19821
- Frances Farmer papers, 1900/19931
- Francis H. Fife papers, 1785/2015, bulk 1940/20151
- George Washington Lewis papers, 1805/19661
- George Wilson and Elizabeth Dent Wilson family photos and memorabilia, 1870/19691
- Jan Karon papers, 1918/2018, bulk 1964/20181
- Jefferson Society records, 1825/20181