- Addison H. Smith papers, 1917/1970, bulk 1917/19221
- Arthur J. Morris memorabilia, 1884/19921
- Beverley R. Tucker papers, 1886/19731
- Call family papers, 1917/19191
- Chisholm Foundation collection on Frank Gardiner Wisner, 1909/19971
- Clarence B. Pearce papers, 1916/19201
- Clay family memorabilia, 1892/19251
- Coleman, Bromm, Kirschmann family papers, 1861/20181
- Cumming Family Papers, 1818/19921
- Eugene Edward Chiles papers, 1915/19221
- Ewing family memorabilia, 1892/19821
- Food and Drug Administration photographs, 1910/20061
- Frances Farmer papers, 1900/19931
- Francis H. Fife papers, 1785/2015, bulk 1940/20151
- George Washington Lewis papers, 1805/19661