- Carol M. Newman, Jr., Papers, 1930/19871
- Carrie T. Sibold Family Papers, 1912/1990, bulk 1974/19901
- Charles Burchard Collection, 1935/19891
- Clarence Paul Miles Papers, 1902/19601
- Claudius Lee Papers, 1887/19541
- Clinton H. Cowgill Collection, 1916/19771
- College of Agriculture and Life Sciences (CALS) Collection, 1900/20011
- Conan W. Vaughan, Jr., Papers, 1923/19921
- Dayton M. Kohler Papers, 1889/19711
- Diploma Collection, 1877/19641
- E. B. Norris Papers, 1928/19551
- Earl H. Hornbarger Collection, 1912/19631
- Earle D. Gregory Collection, 1915/19971
- Edgemont Farm Papers, 1925/19981
- Edmund Welch Hobbs Scrapbook, 1928/19661