- Barraud Family Papers, 1799/1904, bulk 1810/18601
- Bishop James Madison Papers (Photostats), 1777/18121
- C. L. Worthington Papers, 1752/19381
- Charles Campbell Papers, 1743/18961
- College Papers Collection, 1880/19991
- Francis Scott Key Papers, 1779/18421
- Francis Thornton Turner Letter, 17831
- George Washington Papers [in part: photostats, printed copies, typescripts], 1755/19321
- George Wythe Collection, 1779/19271
- Harold Sniffen Bicentennial Collection, 1971/19761
- J.T. McAllister Notebook, I, 1813/18991
- James Madison, Sr. Papers, 1792/19311
- Jean-Baptiste-Donatien de Vimeur, comte de Rochambeau Papers, 1781/17891
- John Littlefield Memorandum Book, 1761/1845, bulk 1761/17821
- John Marshall Papers, 1755/18351