- Bland Family papers, 1778/19891
- Capital Club of Williamsburg Records, 1960/2015, bulk 1970/20001
- Carl A. "Pappy" Fehr papers, 1907/2012, bulk 1945/19741
- Carlton Casey Papers, 1894/19991
- Caskie Stinnett Papers, 1919/1998, bulk 1950/19931
- Charles and William Person Papers, 1900/2011, bulk 1920/19501
- Chisholm Foundation collection on Frank Gardiner Wisner, 1909/19971
- Christopher Wren Singers Records, 1989/2012, bulk 1993/20031
- Circle K International Records, 1958/2009, bulk 1958/19641
- Coleman-Wilson Papers, 1775/1989, bulk 1883/19641
- Colonial Dames of the Commonwealth of Virginia, Susan Constant Committee, 1907/2005, bulk 1936/20051
- Colonial Piecemakers Quilt Guild scrapbook, 1988/20131
- Davis Young Paschall Collection, 1931/2001, bulk 1931/20011
- Delta Sigma Theta Sorority, Inc. Iota Alpha Chapter 50th anniversary collection, 1973/20181
- Department of Living Sciences records, 1915/20031