- A. Willis Robertson Papers, 1921/1988, bulk 1946/19661
- American Association of University Professors, College of William and Mary Chapter Records, 1924/1979, bulk 1924/19791
- American Studies Program Records, 1960/20061
- Armand J. Galfo Papers, 1940/2008, bulk 1958/19951
- Blake W. Corson, Jr., Papers, 1861/1984, bulk 1934/19791
- Board of Visitors records, 1757/20231
- Capital Outlay Records, 1954/19911
- Career Center Records, 1939/2001, bulk 1950/19851
- Chesapeake Western Railway Company Records, 1916/19821
- Circle K International Records, 1958/2009, bulk 1958/19641
- College Papers Collection, 1880/19991
- College of William and Mary Audit Reports Collection, 1934/19881
- Computer Center Records, 1963/20031
- Department of Anthropology records, 1967/2007, bulk 1980/19951
- Department of Fine Arts records, 1930/19981