- Board of Visitors records, 1757/20231
- Campbell Family Papers, 1726/19201
- Collection of French Language Manuscripts, 1633/1942, bulk 1633/19421
- College Papers Collection, 1880/19991
- College Rules Collection, 1849/19551
- E. Lockert Bemiss Papers, 1893/19551
- Eastern State Hospital Records, 1862/1957, bulk 1862/18681
- Genealogy Collection, 1880/20011
- Guy Family Papers, 1900/19881
- James Madison, Sr. Papers, 1792/19311
- Janet C. Kimbrough Williamsburg Area History Collection, 1873/19941
- John Garland Pollard Papers, 1683/1968, bulk 1856/19371
- King's Daughters. Kate Custis Circle (Williamsburg, Va.) Records, 1893/19701
- Lee Family Papers, 1858/1976, bulk 1900/19501
- Marshall-Wythe Institute for Research in Social Science, 1892/1975, bulk 1963/19751