- Blow Family Papers, 1613/1960, bulk 1770/18751
- Borland Family Papers, 1771/19401
- Brown, Coalter, Tucker Papers (I), 1790/19291
- Bucktrout-Braithwaite Papers, 1780/1996, bulk 1890/18991
- Campbell Family Papers II, 1795/19451
- Campbell Family Papers, 1726/19201
- Carpenter Papers, 1765/19221
- Carter Braxton Collection, 1833/1922, bulk 1833/18371
- Civil War Collection, 1856/19381
- Clarence P. Jones, Jr. Papers, 1773/1915, bulk 1809/18211
- Diggs Family Papers, 1914/1960, bulk 1920/19401
- Earl Gregg Swem Family Papers, 1871/19841
- Earl Gregg Swem Genealogy Collection, 1719/19821
- Enoch Strother Papers, 1800/19201
- Farrar Family Papers, 1875/19641