- Charles Brown Papers, 1792/18881
- Charles C. Phillips Civil War papers, 1862/18651
- Charles Howard Papers, 1865/18791
- Civil War Collection, 1856/19381
- Clarence P. Jones, Jr. Papers, 1773/1915, bulk 1809/18211
- Cornelius Smith Papers, 1805/18901
- Crabill Papers, 1842/18841
- Daisy Bacon Papers, 1857/19861
- Daniel Philippe Aunspaugh Papers, 1800/18811
- Daniel Stickley Papers, 1829/19121
- Dromgoole Family Papers, 1821/1896, bulk 1850/18901
- Earl Gregg Swem Genealogy Collection, 1719/19821
- Eldon Bowman collection of Bowman family papers, 1797/20191
- Enoch Strother Papers, 1800/19201
- Evans Tanner Papers, 1830/18801