- Nicolson Family Ledgers and Journals, 1802/19141
- Nineteenth Century Invoices and Receipts Collection, 1804/18891
- Richard Billups Papers, 1705/1857, bulk 1774/18221
- Richard H. Patchin Papers, 1829/1902, bulk 1860/18901
- Riddle Papers, 1812/19151
- Rinker family papers, 1837/19161
- Robert E. Lee and Lee Family papers, 1779/19261
- Robert Stephen papers, 1815/18491
- Rockbridge County, Va. Court Receipt Book, 1833/18551
- Scott Family Papers, 1793/19131
- See Family Papers, 1821/19181
- Sheldon Business Papers and Accounts, 1826/18571
- Skipwith Family papers, 1760/19771
- Southall Papers, 1807/19041
- T. Smith & Company. Records, 1836/18491