- Blow Family Papers, 1613/1960, bulk 1770/18751
- Campbell Family Papers, 1726/19201
- Carter Family Papers, 1667/1862, bulk 1792/18611
- Earl Gregg Swem Genealogy Collection, 1719/19821
- Grigsby-Galt Papers, 1736/1982, bulk 1840/19301
- Harrisonburg-Rockingham Historical Society Collection, 1740/19501
- John Garland Pollard Papers, 1683/1968, bulk 1856/19371
- Lexington Arsenal and Virginia Militia records, 1702/18391
- Mary and Hannah Gibbons Papers, 1743/18901
- Richard Billups Papers, 1705/1857, bulk 1774/18221
- Thomas G. and Louise Rowe Pullen Collection, 1655/17911
- Tucker-Coleman papers, 1664/1945, bulk 1770/19071
- Tyler Family Papers, Group A, 1716/19461
- Upshur Family Papers, 1662/19361
- Virginia Cities Collection, 1663/19801