- Charter Day collection, 1859/20221
- Commencement Exercises collection, 1831/20241
- Earl Gregg Swem Family Papers, 1871/19841
- Edward R. Jones, Jr. Papers, 1861/19921
- Farrar Family Papers, 1875/19641
- Henry Denison Cole Papers, 1786/19391
- Janet C. Kimbrough Williamsburg Area History Collection, 1873/19941
- Jefferson Davis Papers, 1858/19041
- John Tyler Papers, 1840/19311
- Julia W. Oxrieder Papers, 1877/19981
- Matthew Whaley School Collection, 1850/2012, bulk 1880/19601
- Office of the President. Records, 1874/20101
- Person Family papers, 1872/20021
- Rev. Samuel Huntting Sayre, Jr. Papers, 1874/1989, bulk 1920/19601
- Stephen P. Middleton Letter Book and Diary, 1880/18931