- A. Edwin Kendrew Papers, 1930/19591
- Abraham Lincoln Collection, 1860/19651
- Caley Family Papers, 1895/19681
- Carlton Casey Papers, 1894/19991
- Democratic Party Ephemera Collection, 1912/1961, bulk 1912/19281
- Ellinor Porcher Gadsden Papers, 1839/19751
- Ephemera Collection, 1800/20141
- Fay Parr Papers, 1920/20021
- Frances Breeze Music Collection, 1890/19801
- Francis P. Gaines Papers, 1803/19791
- Georgia Ragsdale Curtis Papers, 1912/2002, bulk 1930/19751
- Hamilton Family Papers, 1892/2003, bulk 1930/20031
- Helen L. Johnson Papers, 1925/1982, bulk 1925/19401
- Ivy House Restaurant Records, 1906/1985, bulk 1948/19601
- James Noah Hess Scrapbook, 1920/19401