- E.R. McElligott Papers, 1917/19191
- Earl and Jewell Ratliff Collection, 1860/2013, bulk 1920/19901
- Edith Malleis nursing student scrapbook, 1924/19271
- Edith McChesney Ker papers, 1948/20031
- Edward Utz, Collector, Postcards of West Virginia Subjects, 1905/19401
- Eleanor H. Fredricks Papers
1930-19611
- Eleanor H. Fredricks Papers, 1930/19611
- Eliza Clinedinst Crim correspondence, 1905/19231
- Elsie Ball Wright Bowley Papers, 1929/19721
- Ephemera Collection, 1800/20141
- Ernest L. Frye Papers, 1917/19181
- Etta Evans Scrapbook, 1935/19361