- Quisenberry Family Papers, 1900/19502
- Thomas Putnam Chapman, Jr. Papers, 1875/19352
- African American Family Photographs, 1880/19601
- Anne Christiansen Chapman Scrapbook, 1920/19221
- Arthur W. and Leah James Scrapbooks, 1909/19771
- Bertha Couchman Hess and Ethel Virginia Dunn Correspondence, 1918/19271
- Bettie Hiter Willis Papers, 1864/19421
- Blackley Family papers, 1830/20201
- Carlton Casey Papers, 1894/19991
- Charles T. Smith photographs, 1880/2007, bulk 1990/19991
- Collection of Photographs of Lexington, Va., 1857/19691
- Coray S. Brown family photograph collection, 1910/19601
- Crocker Family Postcards, 1900/19301
- Cynthia Barlowe Collection, 1902/20011
- Earl and Jewell Ratliff Collection, 1860/2013, bulk 1920/19901