- Grigsby-Galt Papers, 1736/1982, bulk 1840/19301
- Gustav Klemp German World War I collection, 1901/19221
- Heatwole Family Papers, 1838/20011
- Henkel Family Papers, 1801/20081
- Howard Chapin Papers, 1882/19401
- J. J. Fahrney Papers, 1886/19361
- John Cuthbert, Collector, Historical West Virginia Materials, 1825/19651
- Larry Jones, Collector, Postcards, Photographs, and Other Material, 1785/1993, bulk 1897/19931
- Natural Tunnel, Scott County, Virginia, Collection, 1872/19581
- Photograph and Postcard of Ann Smith Academy, 1900/19801
- Postcard of Home of James E. A. Gibbs, 1900/19501
- Postcards of the Homestead resort in Bath County, Virginia, 1900/19801
- Quisenberry Family Papers, 1900/19501
- Racial and Ethnic Ephemera Collection, 1778/20051
- Reed Family Papers, 1899/1946, bulk 1910/19461