- Natural Tunnel, Scott County, Virginia, Collection, 1872/19581
- Racial and Ethnic Ephemera Collection, 1778/20051
- Rev. Samuel Huntting Sayre, Jr. Papers, 1874/1989, bulk 1920/19601
- Roane Family Papers, 1880/1973, bulk 19501
- Robert Truax Washington, D.C. transportation collection, 1880/19851
- Ryland Correspondence Collection, 1843/19881
- Shaver and Schaeffer Family Collection, 1872/19771
- Stephens and Yount Family Papers, 1812/19951
- Thomas Connors Collection, 1805/19231
- Thomas Putnam Chapman, Jr. Papers, 1875/19351
- Williamsburg (Va.) Area Ephemera Collection, 1858/20151