- Adam Empie Papers, 1811/2004, bulk 1811/18501
- Alice Hermione Wheaton Literature Journal, 1860/18801
- Benjamin Stoddert Ewell Papers, 1784/1934, bulk 1830/18921
- Brotherton Family Collection, 1854/18871
- Brown, Coalter, Tucker Papers (III), 1838/19641
- C. W. Murdaugh Papers, 1853/18781
- Charles Campbell Papers, 1743/18961
- Civil War Collection, 1856/19381
- Dade-Hansbrough-Patton Papers, 1825/18661
- Ephemera Collection, 1800/20141
- Fletcher Family Papers, 1861/18671
- Gilbert M. Woodward Poem, 18641
- Grigsby-Galt Papers, 1736/1982, bulk 1840/19301
- Hall Family Papers, 1810/20071
- Hart Papers I and II, 1847/19341