- Abraham Anson papers, 1939/20051
- Blackley Family papers, 1830/20201
- Blanche Lazzell, Artist, Papers, 1881/19921
- Booker T. Washington, Commemorative Articles and Other Miscellaneous Items, 1881/19811
- Charles Lietwiler transportation collection, 1903/20051
- Dr. J.C. Easton, History Professor, Papers, 1860/1960, bulk 1935/19601
- Duncan Alexander MacLeod Collection, 1932/19861
- Earl Ray Zinn Papers, 1910/19751
- Ephemera Collection, 1900/1993, bulk 1900/19301
- Frederick H. Stady papers, 1940/19531
- George Kossuth, Photographer, Photographs, 1904/19591
- Gravely and Moore Studio, Photography Business in Charleston, Negatives, 1860/1969, bulk 1930/19451
- Jacob H. Gerbrick, Photographer, Records, 1857/19741
- John Burns Murphy, Compiler, Genealogy of Murphy and Related Families, 1890/19881
- Jolliff Family Papers, 1878/19541