- Alumni Association Records, 1924/20161
- American Association of University Women (AAUW) Records, Harrisonburg, Virginia Branch, 1929/20251
- Anthony-Seeger Campus School Records, 1956/19821
- Betty Brown Clemmer and Willis Clemmer papers, 1920/2015, bulk 1943/19491
- Betty Clougherty Miller papers, 1945/20001
- Betty Coe Cinquegrana papers, 1960/20141
- Blackley Family papers, 1830/20201
- Charles Grattan Price Jr. and Don W. Thomas collection on the Chesapeake Western Railway, 1872/19961
- Charles Grattan Price Jr. collection on Tweetsie and the Shenandoah Central Railroad, 1916/1997, bulk 1948/19561
- Charles T. Smith photographs, 1880/2007, bulk 1990/19991
- Daisy Bacon Papers, 1857/19861
- Davis, Kline, and Hutton Family papers, 1816/19771
- Delphine Hurst Parsons papers, 1923/1976, bulk 1923/19311
- Dennis Pluchinsky collection on terrorism and counterterrorism, 1956/20161
- Department of Living Sciences records, 1915/20031