- David Hunter Notebook, 1830/18401
- David Somervill Notebooks, 1768/17841
- Davis, Kline, and Hutton Family papers, 1816/19771
- Dawson Warren Notebooks, 1822/18281
- Dell Upton Papers 1973-19991
- Draft Counseling Service Records, 1968/19711
- Edgar Woods Notebook, 1851/18711
- Edward C. Shepherd papers, 1851/18551
- Edward M. Watts Notebook1
- Edwin S. Cohen papers, 1924/1995, bulk 1946/19891
- Eleanor Calkins Papers, 1915/1961, bulk 1927/19611
- Elise B. Hardy Papers, 1933/19351
- Elizabeth Van Lew Collection, 1854/19261
- Elizabeth Winston Lanier Papers, 1926/1988, bulk 1975/19881
- Elmon T. Gray collection, 1931/20101