- Hall Family Papers, 1810/20071
- Howard Chapin Papers, 1882/19401
- Howard Scammon Papers, 1917/1994, bulk 1940/19701
- James H. Law, Jr. papers, 1920/19211
- James M. Owens Collection of Madison Family Material, 1776/19531
- Jennings C. Wise papers, 1910/19601
- John Lesslie Hall Papers, 1885/19281
- John Lesslie Hall, Jr. Papers, 1893/19731
- John Roberts Fisher Papers, 1910/19281
- Lee Family Papers, 1858/1976, bulk 1900/19501
- Lee Nicholson Papers, 1827/19381
- Lewis Peyton Little Papers, 1918/19361
- Morton Genealogical Inquiries Collection, 1844/19601
- Morton Genealogy Collection, 1830/19781
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/19745