- Baird Family Papers, 1656/1922, bulk 1656/18481
- Charles H. Bell Papers, 1772/1929, bulk 1852/18751
- David Somervill Notebooks, 1768/17841
- Fairfax Harrison Papers, 1736/19451
- John Page Memorandum Book, 1762/17971
- John Sublet Arithmetic Book, 1766, 1816, 1766/18161
- John Womack Wright Collection of Maps, 1675/19181
- Mary and Hannah Gibbons Papers, 1743/18901
- Robertson Family Papers, 1730/19501
- Robinson Family Papers, 1725/1940, bulk 1793/18481
- Sir Jeffray Gilbert Notes, 1750/18001
- Tyler Family Papers, Group H, 1750/19351
- University Archives Bound Volumes Collection, 1693/19931
- Upshur Family Papers, 1662/19361
- W. Wilson Notebook, 1755/17991