- Campbell Family Papers, 1843/19501
- Channing M. Hall III Williamsburg, Virginia Papers, 1996/20041
- Charles A. Derby papers, 1839/18911
- Charles A. Veatch papers, 1970/20041
- Charles P. Deyerle papers, 1842/18552
- Chester McNerney Collection, 1290/19501
- Delphine Hurst Parsons papers, 1923/1976, bulk 1923/19311
- Dennis Pluchinsky collection on terrorism and counterterrorism, 1956/20161
- Don (Donald H.) Amador Papers, 1944/19831
- Drew Nemser Conger George Mason College collection1
- Ebenezer Dickey Junkin Scrapbook, 1853/18561
- Edward M. Peach historical newspaper collection1
- Edwin W. Lynch Vietnam War protest collection, 1965/19751
- Effinger School Collection, 1909/201127
- Elizabeth Nunn Papers, 1931/19751