- A. Edwin Kendrew Papers, 1930/19591
- Academic Departments - Record Group 91
- Alexander Haight family collection, 1764/19761
- C-SPAN records, 1809/2012, bulk 1978/20121
- C. Harrison Mann, Jr. papers, 1832/19791
- Campbell Family Papers, 1843/19501
- Chester McNerney Collection, 1290/19501
- Delphine Hurst Parsons papers, 1923/1976, bulk 1923/19311
- Effinger School Collection, 1909/20111
- Ephemera Collection, 1800/20141
- Fay Parr Papers, 1920/20021
- Fred Frechette Papers, 1930/2000, bulk 1950/20001
- Guy Family Papers, 1900/19881
- James Madison Memorabilia, 1796/19511
- Jane Ayers Davis Collection, 1909/1932, bulk 1909/19321