- B. Floyd Flickinger Papers, 1927/19501
- Benjamin Waller Account Book, 1803/18331
- Blake W. Corson, Jr., Papers, 1861/1984, bulk 1934/19792
- Board of Visitors records, 1757/20231
- Bowles Family Papers, 1827/18701
- Center for Student Diversity Records, 1975/20131
- Charles Brown Papers, 1792/18881
- Charles Grattan Price Jr. collection on Tweetsie and the Shenandoah Central Railroad, 1916/1997, bulk 1948/19561
- College Laundry Records, 1950/1955, bulk 1950/19551
- Committees Collection, 1921/20121
- Evening College Reference Collection, 1919/19621
- Faculty Assembly Records, 1729/20081
- Faculty Circulars, 1922/19751
- Faculty Organizations Collection, 1930/19991
- Francis Scott Key Papers, 1779/18421