- Austin-Twyman Papers, 1765/19391
- Carl R. Dolmetsch Papers, 1751/19901
- Chappelear Collection, 1788/19591
- Dismal Swamp Collection, 1763/19281
- Francis P. Lee Papers, 1727/19301
- Frank Snowden Hopkins papers, 1905/19951
- Galen W. Ewing Papers, 1840/1938, bulk 1840/19381
- Galt Papers (III), 1750/19911
- Hall Family Papers, 1810/20071
- Harold B. Meyers papers, 1909/20211
- Henry Eastman Bennett Papers, 1907/1936, bulk 1907/19271
- J. Luther Kibler Papers, 1908/19441
- James Barron Hope Papers (I), 1790/1965, bulk 1847/18871
- James Barron Hope Papers (II), 1820/19231
- James M. Owens Collection of Madison Family Material, 1776/19531