- John Lesslie Hall, Jr. Papers, 1893/19731
- John Tayloe Perrin Papers, 1770/19311
- John Walter Wayland Papers, 1892/19401
- Lee Nicholson Papers, 1827/19381
- Literary Addresses, Articles, Essays, Poetry and Short Stories, 1808/19381
- Marshall-Wythe Institute for Research in Social Science, 1892/1975, bulk 1963/19751
- Office of the President. Lyon Gardiner Tyler Records, 1888/19351
- Page-Saunders Papers, 1790/19321
- Robert Morton Hughes College Papers, 1870/19181
- Robert Southall Bright Papers, 1906/19411
- Silas Totten Papers, 1845/19161
- Tyler Family Papers, Group B, 1868/19511
- Tyler Family Papers, Group E, 1880/1951, bulk 1880/19351
- Tyler Family Papers, Group G, 1645/19171
- Upshur Family Papers, 1662/19361