- Barton Myers Papers, 1878/19251
- Caskie Stinnett Papers, 1919/1998, bulk 1950/19931
- Charles Grattan Price Jr. collection on Tweetsie and the Shenandoah Central Railroad, 1916/1997, bulk 1948/19561
- Dennis Pluchinsky collection on terrorism and counterterrorism, 1956/20161
- Elizabeth "Libby" Custer Papers, 1930/19971
- Kathryn Eye Papers, 1920/19911
- Lips Zine Records, 2007/20121
- Print Collection, 1740/19401
- Sister Speak records, 1998/20191
- William & Mary Hip Hop collection, 1985/2019, bulk 2012/20141
- Zeta Upsilon Chapter of Sigma Chi records, 1966/19681