- Independence, Virginia Quadrangle, 19441
- Independent Order of St. Luke Records, 1877/19701
- Index to Fee Book (Montgomery County, VA), 1850/18571
- Index to Topographic Maps and Geologic Folios, Virginia, 19181
- Indian Valley, Virginia Quadrangle, 19681
- Industrial Education Association for Southern Mountaineers Collection, 1930/19361
- Ingles Family Collection, 1797/18231
- Irish Creek Property of the Misses Davidson [Rockbridge County], 18911
- Iron Gate, Virginia, Ledgers, 1892/19311
- Isaac Cox Letter, 18621
- Isaac Horne Ledgers, 1824/18701
- Isaac White Letters, 1861/19381
- Isabella J. "Bell" McCauley Letters, 18601
- Ivanhoe Mining & Smelting Corporation, Riverside Mines, Washington County, Virginia, 19511
- Ivanhoe Mining and Smelting Corp'n Riverside Mine, Washington County, Virginia, 19521