- Records of the American Association of University Women (AAUW), Virginia Tech Chapter, 1926/20081
- Rick Boucher Papers, 1968/2017, bulk 1975/20111
- Roanoke Appalachian Trail Club Records, 20251
- Roanoke Valley Academy of Medicine Records, 1874/20161
- Southside Garden Club Records, 1914/20091
- The Reverend Dr. and Mrs. Richard Eugene Hager (Anne Peyton Judkins Hager) Collection, 1802/20071
- Thomas David Perry Collection, 1979/20071
- United Daughters of the Confederacy, Dr. Harvy Black Chapter Records, 1862/20101
- Virginia Association of Educational Opportunity Program Personnel (VAEOPP) Records, 1970/20151
- Virginia Extension Homemakers Council Papers, 1948/20071
- Virginia Tech April 16, 2007 Archives of the University Libraries, 2007/20101
- Virginia Tech Buildings Architectural Collection, 1907/2011, bulk 1953/19961