- Abraham Anson papers, 1939/20051
- Chapman Family Collection (MS274), 1828/19631
- James M. Buchanan papers, 1920/20131
- Jerome Epstein papers, 1943/19831
- McKnight, Piercy, and Jacobs Collection (MS051), 1792/19731
- Nicholas Colasanto Collection (MS035), 1947/19801
- Randolph H. Lytton Historical Virginia collection, 1670/20041
- Royd R. Sayers Collection (MS094), 1932/19681
- Shakes Letter Collection (MS005), 1778/20151
- Tulloch Papers (MS250), 1889/19921
- Whitton Collection (MS027), 1843/19892