- Davidson Family Papers, 1773/19381
- Dew Family papers, 1794/18951
- Dromgoole Family Papers, 1821/1896, bulk 1850/18901
- Edson J. Harkness Papers, 1827/18651
- Eldon Bowman collection of Bowman family papers, 1797/20191
- Evans Tanner Papers, 1830/18801
- Fairfax Harrison Papers, 1736/19451
- Francis Little Collection, 1770/18641
- Francis P. Lee Papers, 1727/19301
- Francis Wilkinson Pickens collection, 1826/18651
- Galt Papers (III), 1750/19911
- Galt Papers (IV), 1819/18751
- Garth Family papers, 1798/18721
- Geddy-Harris Archive Records, 1773/1959, bulk 1890/19401
- George Wythe Collection, 1779/19271