- Adams Papers, 1782/18901
- Anderson Family papers, 1755/19581
- Andrew Lindamood papers, 1768/18171
- Austin-Twyman Papers, 1765/19391
- Baird Family Papers, 1656/1922, bulk 1656/18481
- Bland Family papers, 1778/19891
- Brafferton Estate Collection, 1691/19351
- Britt Family Papers, 1801/18601
- Brown, Coalter, Tucker Papers (I), 1790/19291
- Bucktrout-Braithwaite Papers, 1780/1996, bulk 1890/18991
- C. L. Worthington Papers, 1752/19381
- Cabaniss Family Papers, 1800/18371
- Cabell Family Papers, 1693/1913, bulk 1743/18231
- Campbell Family Papers II, 1795/19451
- Campbell Family Papers, 1726/19201