- Baird Family Papers, 1656/1922, bulk 1656/18481
- Brafferton Estate Collection, 1691/19351
- Cabell Family Papers, 1693/1913, bulk 1743/18231
- Carter Family Papers, 1667/1862, bulk 1792/18611
- Collection of Spanish Language Manuscripts, 1551/18581
- Manuscripts - People and Family Names, 1621/1949, bulk 18001
- Office of the President. James Blair Records, 1695/17471
- Richard Billups Papers, 1705/1857, bulk 1774/18221
- Richard G. Joynt Collection of British Manuscripts, 1593/20151
- Robb-Bernard Papers, 1665/1980, bulk 1850/19501
- Royal Court of Guernsey Contracts, 1675/17061
- Short Papers, 1675/17891
- Stanford Family Legal Papers, 1639/17201
- Tucker-Coleman papers, 1664/1945, bulk 1770/19071
- Upshur Family Papers, 1662/19361