- Charter Day collection, 1859/20221
- Colonial Festival Collection, 1921/19611
- Commencement Exercises collection, 1831/20241
- Department of Home Economics Records, 1921/19711
- Department of Military Science Records, 1918/20111
- Dorothy E. Howe Scrapbooks, 1923/19271
- Ephemera Collection, 1800/20141
- Guy Family Papers, 1900/19881
- James Madison, Sr. Papers, 1792/19311
- John Branch Green Papers, 1924/19291
- John Tyler, Jr. Papers, 1800/19281
- Matthew Whaley School Collection, 1850/2012, bulk 1880/19601
- Mr. and Mrs. Donald W. Davis Collection, 1911/1994, bulk 1911/19441
- Myers-Burrage-Graham papers (I), Group A, 1776/19251
- Schuyler Otis Bland Papers, 1862/19501