- Archibald Woods Papers, 1777/1846, bulk 1783/18461
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Charles L. Campbell (b. 1876), Compiler, Typescripts, 1789/19561
- Cleaver Family Papers, 1777/19691
- Grigsby-Galt Papers, 1736/1982, bulk 1840/19301
- Henderson and Tomlinson Families Papers, 1789/18591
- J.C. Sanders, Collector, Papers, 1700/19501
- Leven Powell papers, 1774/18061
- Lyman C. Draper, Antiquarian, Manuscripts, 1740/18151
- McGavock Family Papers, 1760/18881
- Racial and Ethnic Ephemera Collection, 1778/20051
- Vida Bailey, Collector, Papers, 1790/18821