- Booton-Modesitt Family Papers, 1809/1880, bulk 1820/18501
- Borland Family Papers, 1771/19401
- Bozarth Family Papers, 1931/1985, bulk 1931/19621
- Brafferton Estate Collection, 1691/19351
- Britt Family Papers, 1801/18601
- Brown, Coalter, Tucker Papers (I), 1790/19291
- Brown, Coalter, Tucker Papers (II), 1791/19201
- Brown, Coalter, Tucker Papers (III), 1838/19641
- Buford Family Papers, 1845/18951
- Burwell Family Papers, 1853/19111
- Byers Family Papers, 1806/19291
- C. L. Worthington Papers, 1752/19381
- Cabaniss Family Papers, 1800/18371
- Calfee Family Papers, 1812/1919, bulk 1859/18891
- Campaign for the College Records, 1975/1978, bulk 1975/19761