- Byers Family Papers, 1806/19291
- C. L. Worthington Papers, 1752/19381
- Calfee Family Papers, 1812/1919, bulk 1859/18891
- Campbell Family Papers II, 1795/19451
- Campbell Family Papers, 1726/19201
- Carpenter Papers, 1765/19221
- Charles D. Tibbetts Papers, 1848/19321
- Civil War Collection, 1856/19381
- College Papers Collection, 1880/19991
- Daniel Stickley Papers, 1829/19121
- Darby-Parramore Papers, 1801/19081
- Dora and Cara Armistead Papers, 1880/19501
- Earl Gregg Swem Family Papers, 1871/19841
- Earl Gregg Swem Genealogy Collection, 1719/19821
- Enoch Strother Papers, 1800/19201