- Alabama Collection, 1823/18931
- Alexander Brown Papers (I), 1815/19101
- Alexander M. Davis Papers, 1850/18921
- Armistead-Cocke Papers, 1680/19171
- Armstrong Family Papers, 1853/19031
- Augustus C. Golding Papers, 1859/1934, bulk 1862/18641
- Baker Family Papers, 1805/19111
- Barker-Cooke Papers, 1809/1889, bulk 1848/18661
- Barron Family Papers, 1793/19421
- Benjamin Stoddert Ewell Papers, 1784/1934, bulk 1830/18921
- Blair, Banister, Braxton, Horner, Whiting Papers, 1760/1890, bulk 1765/18171
- Blakemore Papers, 1830/18891
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Borland Family Papers, 1771/19401
- Brafferton Estate Collection, 1691/19351