- Alfred C. Payne Collection, 1917/20031
- Ann A. Hertzler Collection, 1863/2013, bulk 1974/20001
- Dean Carter Papers, 1950/2003, bulk 1964/19821
- Department of Biochemistry Oral History Collection, 2001/20051
- Doris Zallen Papers, 1952/20161
- Dr. Richard Zallen Papers, 1940/20071
- Elizabeth Fine Papers, 1983/20121
- G. Preston Frazer Collection, 1939/20031
- Hard Times Blues Collection, 1966/20191
- Henry H. Bauer Papers, 1950/20101
- Irving J. Good Papers, 1925/20041
- James I. Robertson Jr. Papers, 1849/20111
- Jean Elliott Papers, 1999/20151
- John M. and Cora Bolton McBryde Family Papers, 1862/20181
- Larry McBryde Collection on the John McLaren McBryde Family, 1859/20131