- A. Franklin Kibler papers, 1943/19521
- A. H. Hand Papers, 1835/20091
- A. Willis Robertson Papers, 1921/1988, bulk 1946/19661
- Abraham Anson papers, 1939/20051
- Albert D. Davis papers, 1930/19521
- Albert S. Britt, Jr. papers, 1930/19621
- Alexander Haight family collection, 1764/19761
- Alexander Kallos Papers, 1939/19591
- Allen Wesley Moger Correspondence, 1943/19451
- Allen-Kean-Laurence family letters, 1837/19601
- Althea Hunt Papers, 1926/19611
- Alumni Association Records, 1833/2014, bulk 1950/20051
- Alvin Duke Chandler Papers, 1896/1984, bulk 1950/19601
- American Association of University Professors, College of William and Mary Chapter Records, 1924/1979, bulk 1924/19791
- American Public Transportation Association records, 1898/19991