- A. H. Hand Papers, 1835/20091
- A. K. Leake Papers, 1872/19401
- A. Willis Robertson Papers, 1921/1988, bulk 1946/19661
- Albert C. Swindler Papers, 1862/1929, bulk 1862/18641
- Alexander Farish Robertson Papers, 1867/19311
- Alexander Haight family collection, 1764/19761
- Allen-Kean-Laurence family letters, 1837/19601
- Althea Hunt Papers, 1926/19611
- Alumni Association Records, 1833/2014, bulk 1950/20051
- Alvin Duke Chandler Papers, 1896/1984, bulk 1950/19601
- American Association of University Professors, College of William and Mary Chapter Records, 1924/1979, bulk 1924/19791
- American Public Transportation Association records, 1898/19991
- Ammen L. Burger, Jr. collection, 1917/19601
- Amos Koontz Papers I, 1809/1965, bulk 1936/19651
- Amos Koontz Papers II, 1865/19701