- A. H. Hand Papers, 1835/20091
- A. K. Leake Papers, 1872/19401
- A. Willis Robertson Papers, 1921/1988, bulk 1946/19661
- Albert C. Swindler Papers, 1862/1929, bulk 1862/18641
- Allen-Kean-Laurence family letters, 1837/19601
- Alumni Association Records, 1833/2014, bulk 1950/20051
- Alvin Duke Chandler Papers, 1896/1984, bulk 1950/19601
- American Association of University Professors, College of William and Mary Chapter Records, 1924/1979, bulk 1924/19791
- Amos Koontz Papers I, 1809/1965, bulk 1936/19651
- Amos Koontz Papers II, 1865/19701
- Anatole and Vladimir Kalichevsky Papers, 1871/19551
- Anne T. Chapman Papers, 1884/19541
- Anson Du Puy Van Buren letters, 1863/19971
- Arthur George Williams Scrapbooks, 1905/19351
- Association for the Preservation of Virginia Antiquities, Colonial Capitol Branch Records, 1896/19891