- Allen-Kean-Laurence family letters, 1837/19601
- Alumni Association Records, 1833/2014, bulk 1950/20051
- American Civil War collection, 1860/18951
- Amos Koontz Papers I, 1809/1965, bulk 1936/19651
- Amos Koontz Papers II, 1865/19701
- Anatole and Vladimir Kalichevsky Papers, 1871/19551
- Anderson Family papers, 1755/19581
- Andrew C. L. Gatewood papers, 1860/19931
- Ann Smith Academy Papers, 1807/19101
- Anne T. Chapman Papers, 1884/19541
- Anson Du Puy Van Buren letters, 1863/19971
- Armistead Boothe Papers (MS164), 1803/19901
- Armistead-Cocke Papers, 1680/19171
- Armstrong Family Papers, 1853/19031
- Augustus C. Golding Papers, 1859/1934, bulk 1862/18641