- A. H. Hand Papers, 1835/20091
- A. K. Leake Papers, 1872/19401
- Abolitionist Movement Collection, 1834/18881
- Adams Papers, 1782/18901
- Alabama Collection, 1823/18931
- Albert C. Swindler Papers, 1862/1929, bulk 1862/18641
- Albert P. Bourland Letter, 18851
- Alexander Brown Papers (I), 1815/19101
- Alexander Brown Papers (II), 1748/19001
- Alexander Hamilton, Jr. Letters, 1832/18331
- Alexander M. Davis Papers, 1850/18921
- Alfred E. Bradley Papers, 1864/1922, bulk 1916/19181
- Allen-Kean-Laurence family letters, 1837/19601
- Alumni Association Records, 1833/2014, bulk 1950/20051
- Amos Koontz Papers I, 1809/1965, bulk 1936/19651