- Adams Papers, 1782/18901
- Alexander Brown Papers (II), 1748/19001
- Alexander Haight family collection, 1764/19761
- Anderson Family papers, 1755/19581
- Archibald Stuart Papers, 1790/18161
- Archibald Woods Papers, 1777/1846, bulk 1783/18461
- Armistead-Cocke Papers, 1680/19171
- Austin-Twyman Papers, 1765/19391
- Baer Family Papers, 1744/19291
- Baird Family Papers, 1656/1922, bulk 1656/18481
- Barron Family Papers, 1793/19421
- Benjamin Stoddert Ewell Papers, 1784/1934, bulk 1830/18921
- Beverley Papers, 1796/18341
- Bevill Family Papers, 1558/1939, bulk 1558/17071
- Bishop James Madison Papers (Photostats), 1777/18121