- David A. Bucher Papers, 1769/19121
- Davidson Family Papers, 1773/19381
- Dismal Swamp Collection, 1763/19281
- Dunmore Family Papers (I) [in part photocopies], 1650/18991
- Earl Gregg Swem Genealogy Collection, 1719/19821
- Fairfax Harrison Papers, 1736/19451
- Floyd-Johnston-Preston Papers, 1753/19401
- Francis Little Collection, 1770/18641
- Francis P. Lee Papers, 1727/19301
- Francis Scott Key Papers, 1779/18421
- Francois Anselme de Saint-Victor Letter to Mr. d'Eyroux Pontevez a St. Maisme, 17811
- Galt Papers (I), 1745/18921
- Galt Papers (III), 1750/19911
- George Mason Papers, 1706/18581
- George Washington Papers [in part: photostats, printed copies, typescripts], 1755/19321