- Borland Family Papers, 1771/19401
- Brafferton Estate Collection, 1691/19351
- Bucktrout-Braithwaite Papers, 1780/1996, bulk 1890/18991
- C. L. Worthington Papers, 1752/19381
- Cabell Family Papers, 1693/1913, bulk 1743/18231
- Campbell Family Papers, 1726/19201
- Carl R. Dolmetsch Papers, 1751/19901
- Carpenter Papers, 1765/19221
- Carter Family Papers, 1667/1862, bulk 1792/18611
- Chapin collection of Washington & Custis family documents, 1758/18292
- Charles Campbell Papers, 1743/18961
- Charles H. Bell Papers, 1772/1929, bulk 1852/18751
- Coleman-Wilson Papers, 1775/1989, bulk 1883/19641
- Colvin Papers, 1734/18391
- Conway Whittle Papers, 1773/1911, bulk 1801/18671